提供商：Silverchair数据库：theassociationForresearchInvisionInvisionandophthalmology content：text/plain;charset =“ utf -8” ty -jour au -delori，f c au -dorey，c k au -staurenghi，g au -au -arend，o au -au -au -goger，d g au -weiter，j j t1- j j t1- ocular fillus展览的体内荧光视网膜色素上皮脂蛋白特性。PY -1995 Y1-1995/03/01 JO-调查性眼科和视觉科学JA-投资。眼科。VIS。科学。VL -36 IS -3 SP -718 EP -729 SN -1552-5783 AB-目的：以人眼底的激发和发射光谱，年龄关系，视网膜位置和视网膜位置，和人类的发射光谱，和固有的荧光（自动荧光）表征地形，并确定眼底层之间的主要荧光团。方法：使用新型的眼底分光光度计，在30名正常受试者和3名选定患者中，在Fovea和Fovea处于Fovea和Fovea的7度时进行荧光测量。 Topographic measurements were made in 3 subjects. Ex vivo measurements of fluorescence of human retinal pigment epithelium (RPE) were obtained and compared to in vivo data. RESULTS: Fundus fluorescence reveals a broad band of emission between 500 and 750 nm, a maximum of approximately 630 nm, and optimal excitation of approximately 510 nm. Exhibiting a significant increase with age, this fluorescence is highest at 7 degrees to 15 degrees from the fovea, shows a well-defined foveal minimum, and decreases toward the periphery. In vivo fluorescence spectra are consistent with those obtained ex vivo on human RPE. Measurements with short wavelength excitation are strongly influenced by ocular media absorption and reveal an additional minor fluorophore in the fovea. CONCLUSIONS: Spectral characteristics, correlation with age, topographic distribution, and retinal location between the choriocapillaris and the photoreceptors suggest that the dominant fundus fluorophore is RPE lipofuscin. The minor fluorophore is probably in the neurosensory retina but has not been identified. Y2 - 1/17/2022 ER -